AWARD NUMBER: W81XWH-12-1-0352 TITLE: Tribosupplementation with Lubricin in Prevention of Post-Traumatic Arthritis PRINCIPAL INVESTIGATORS:

1. Dorosz, S., Abubacker, S., Masala, N., Jay, G., Schmidt TA. Cartilage Boundary Lubricating Ability of Full-Length Human Recombinant PRG4 – Alone and in Combination with Hyaluronan. March 28-31, 2015. Las Vegas, NV. 2. Al-Sharif A., Schmidt T., Jay G., Elsaid K. Lubricin/Proteoglycan-4 Inhibits Proinflammatory Cytokine Induced Synoviocyte Proliferation via CD44-Interaction. Orthopedic Research Society. March 28-31, 2015. Las Vegas, NV. 3. Jamal M., Schmidt T., Jay G., Elsaid K. Lubricin/Proteoglycan-4 Binding to Cluster Determinant-44 (CD 44) Receptor and The Contribution of Central Mucin Domain Glycosylations. Orthopedic Research Society. March 28-31, 2015. Las Vegas, NV. 4. Larson, K., Elsaid, K., Schmidt, T., Fleming, B., Jay, GD. Tribology of IL-1 Stimulated Cartilage Explants: Restoration of Chondroprotection by rhPRG4. Military Health Research Symposium. August 18-21, 2015, Ft. Lauderdale, FL. 5. Waller KA, Teeple E, McAllister SC, Schmidt TA, Jay GD, Fleming BC: Intra-articular rhPRG4 Mitigates Cartilage Damage Following DMM in a Porcine Model. Orthopaedic Research Society, Orlando, 5-8 March 2016. 6. Larson K, Elsaid K, Schmidt T, Fleming BC, Jay GD: Restoration of PRG4 mRNA and Chondroprotection by rhPRG4 in IL-1α Stimulated Cartilage Explants. Orthopaedic Research Society, Orlando, 5-8 March 2016. 7. Waller K, Zhang L, Teeple E, McAllister S, Schmidt T, Fleming BC, Jay GD: Recombinant Lubricin Reduces Joint Damage and Inflammation Following Traumatic Injury. Osteoarthritis Research Society International, Amsterdam, 30 March – 3 April 2016.